Karst terranes provide unique challenges to professionals faced with characterizing, managing, and remediating sites impacted by regulated substances. Groundwater flow and chemical transport in karst may be complicated by conduits that are difficult to locate, turbulent flow, extreme geologic heterogeneity, dual-porosity and dual-permeability regimes, and sediment transport. Because of these complexities, widespread knowledge and understanding of contaminant hydrogeology of karst is limited. Furthermore, up to 25% of the world’s population depends on waters derived from karst aquifers. This intermediate-level short course focuses on contaminant hydrogeology of karst and is intended for participants who already have a basic understanding of hydrogeology. The target audience is professionals faced with or interested in the subject.